Welcome to the Amira-Avizo Software Use Case Gallery

Below you will find a collection of use cases of our 3D data visualization and analysis software. These use cases include scientific publications, articles, papers, posters, presentations or even videos that show how Amira-Avizo Software is used to address various scientific and industrial research topics.

Use the Domain selector to filter by main application area, and use the Search box to enter keywords related to specific topics you are interested in.

Assessment of effective elastic properties and residual stresses in directionally solidified eutectic Al2O3/YAG/ZrO2 ceramics by finite element analysis

Assessment of effective elastic properties and residual stresses in directionally solidified eutectic Al2O3/YAG/ZrO2 ceramics by finite element analysis

Current materials such nickel based superalloys cannot be used anymore and new materials are thus considered. For the hottest parts of jet engines, eutectic ceramics have potentially interesting features. In order to assess the thermo-mechanical properties of this material, numerical multi-scale analyses may be performed. Thus, a 3D finite element model was generated from a CT scan, representative of the microstructure and with a similar volume fraction. Effective elastic properties were calc... Read more

S. Gourdin, L. Marcin, M. Podgorski, M. Cherif, L. Carroz

Read full paper
Air-entrained Concrete: Relationship between Thermal Conductivity and Pore Distribution Analyzed by X-Ray Tomography

Air-entrained Concrete: Relationship between Thermal Conductivity and Pore Distribution Analyzed by X-Ray Tomography

The thermal conductivity values of ordinary concrete can be adjusted to those prescribed in constructions by entraining air bubbles to reduce the density of concrete in order to achieve good thermal insulation. This paper concerns the analysis of air bubble distribution in concrete obtained by micro X-ray µCT (computed tomography) and correlates it with its thermal conductivity (k). (…) The results show that air-entrainment leads to viable use of this material as sealer to achieve good... Read more

A. P. Peruzzi, J. A. Rossignolo and H. Kahn

Read full paper
Hyperpolarized 13C MR metabolic imaging can detect neuroinflammation in vivo in a multiple sclerosis murine model

Hyperpolarized 13C MR metabolic imaging can detect neuroinflammation in vivo in a multiple sclerosis murine model

Proinflammatory mononuclear phagocytes (MPs) play a crucial role in the progression of multiple sclerosis (MS) and other neurodegenerative diseases. Despite advances in neuroimaging, there are currently limited available methods enabling noninvasive detection of MPs in vivo. Interestingly, upon activation and subsequent differentiation toward a proinflammatory phenotype MPs undergo metabolic reprogramming that results in increased glycolysis and production of lactate. Hyperpolarized (HP) Read more

Caroline Guglielmetti, Chloé Najac, Alessandro Didonna, Annemie Van der Linden, Sabrina M. Ronen, and Myriam M. Chaumeil

Read full paper
Loss of adult skeletal muscle stem cells drives age-related neuromuscular junction degeneration

Loss of adult skeletal muscle stem cells drives age-related neuromuscular junction degeneration

Neuromuscular junction degeneration is a prominent aspect of sarcopenia, the age-associated loss of skeletal muscle integrity. Previously, we showed that muscle stem cells activate and contribute to mouse neuromuscular junction regeneration in response to denervation (Liu et al., 2015). Here, we examined gene expression profiles and neuromuscular junction integrity in aged mouse muscles, and unexpectedly found limited denervation despite a high level of degenerated neuromuscular junctions. In... Read more

Wenxuan Liu, Alanna Klose, Sophie Forman, Nicole D Paris, Lan Wei-LaPierre, Mariela Cortés-Lopéz, Aidi Tan, Morgan Flaherty, Pedro Miura, Robert T Dirksen, Joe V Chakkalakal

Read full paper
Micron-scale crack propagation in laser-irradiated enamel and dentine studied with nano-CT

Micron-scale crack propagation in laser-irradiated enamel and dentine studied with nano-CT

The aim of this study was to see the effect of Er:YAG laser irradiation in dentine and compare this with its effect in enamel. The mechanism of crack propagation in dentine was emphasised and its clinical implications were discussed. A possible mechanism is that laser radiation is transmitted down the dentinal tubules causing micro-cracks to form in the dentinal tubule walls that tend to be limited to this region. Crack might be a source of fracture as it represents a weak point and subsequen... Read more

Abtesam Aljdaimi, Hugh Devlin, Mark Dickinson, Timothy Burnett, Thomas J. A. Slater

Read full paper
Revisiting the lacquer peels method with pyroclastic deposits: sediment plates, a precise, fine scale imaging method and powerful outreach tool

Revisiting the lacquer peels method with pyroclastic deposits: sediment plates, a precise, fine scale imaging method and powerful outreach tool

Sediment plates (a type of lacquer peels) represent a sampling method whereby a thin plate of undisturbed sediments is obtained directly from the outcrop. A low-viscosity, hardening epoxy resin is applied to a freshly exposed cross-section of an unconsolidated deposit and impregnates a surface layer of the cross-section via capillary forces before solidifying. Upon hardening, a solid plate (0.5–5 cm thick and up to 2 m in length) of the sedimentary formation can be recovered and transported... Read more

Guilhem Amin Douillet, Ulrich Kueppers, Célia Mato, Quentin Chaffaut, Mélanie Bouysson, Renate Reschetizka, Inga Hoelscher, Patrick Witting, Kai-Uwe Hess, Alexander Cerwenka, Donald B Dingwell and Benjamin Bernard

Read full paper
Investigation of pressure drop in 3D replicated open-cell foams: Coupling CFD with experimental data on additively manufactured foams

Investigation of pressure drop in 3D replicated open-cell foams: Coupling CFD with experimental data on additively manufactured foams

Open-cell foams as structured catalyst supports are promising candidates for the design of high throughput catalytic processes. In this contribution, we employ a coupled numerical and experimental approach to assess the pressure losses in foams. (…) we explore virtually-generated foam models and their 3D printed replicas for a combined CFD and experimental study of fluid dynamics in foams. In particular, we focus our analysis on the low Reynolds number regime, where deviations between t... Read more

Mauro Bracconi, Matteo Ambrosetti, Obinna Okafor, Victor Sans, Xun Zhang, Xiaoxia Ou, Claudio Pereira Da Fonte, Xiaolei Fan, Matteo Maestri, Gianpiero Groppi, Enrico Tronconi

Read full paper
Vascular structure of the earliest shark teeth

Vascular structure of the earliest shark teeth

Here we use synchrotron tomography to characterise dental vasculature in the oldest known tooth-bearing sharks, Leonodus carlsi Mader, 1986 and Celtiberina maderi Wang, 1993. Three dimensional reconstruction of the vascular system and microstructure of both taxa revealed a complex and dense network of canals, including horizontal, ascending and secondary bifurcated canals, as well as histological features consistent with an osteodont histotype. However, L. carlsi and C. maderi also exhibit si... Read more

Carlos Martinez-Perez, Alba Martin-Lazaro, Humberto G Ferron, Martina Kirstein, Philip C.J. Donoghue, Hector Botella

Read full paper
Nonuniformity in ligaments is a structural strategy for optimizing functionality

Nonuniformity in ligaments is a structural strategy for optimizing functionality

Ligaments serve as compliant connectors between hard tissues. In that role, they function under various load regimes and directions. The 3D structure of ligaments is considered to form as a uniform entity that changes due to function. The periodontal ligament (PDL) connects the tooth to the bone and sustains different types of loads in various directions. Using the PDL as a model, employing a fabricated motorized setup in a microCT, we demonstrate that the fibrous network structure with... Read more

Gili R. S. Naveh, Jonathan E. Foster, Tomas M. Silva Santisteban, Xianrui Yang, and Bjorn R. Olsen

Read full paper
Functional Electrical Stimulation Leads to Increased Volume of the Aged Thyroarytenoid Muscle

Functional Electrical Stimulation Leads to Increased Volume of the Aged Thyroarytenoid Muscle

A stimulation electrode was placed unilaterally near the terminal adduction branch of the recurrent laryngeal nerve (RLN) adjacent to the right cricothyroid joint. The electrode was connected to an implant located subcutaneously at the neck region. Predesigned training patterns were automatically delivered by a bidirectional radio frequency link using a programming device and were repeated automatically by the implant every other day over 11 weeks in the awake animal. Outcome parameters compr... Read more

Markus Gugatschka, MD, DMSci, Jonathan C. Jarvis, PhD, Justin D. Perkins, MSc, Vladimir Bubalo, PhD, Iris Wiederstein-Grasser, PhD, Hermann Lanmüller, PhD, Claus Gerstenberger, MSc and Michael Karbiener, PhD

Read full paper
Two-fluid model to simulate metal powder bed fusion additive manufacturing

Two-fluid model to simulate metal powder bed fusion additive manufacturing

This paper reports our simulations of the metal powder fusion additive manufacturing process based on a two-fluid model. In simulations of metal behavior in which heat is applied by high-density energy sources (e.g., laser or electron beam), the aspects that need to be correctly modeled include boiling and evaporation, as well as melting and solidification. The potential of the two-fluid model to clarify numerous physical phenomena—deep penetration, plume generation, spatter generation due ... Read more

Noriko WATARI, Yuzuru OGURA, Noriko YAMAZAKI, Yukihiko INOUE, Keisuke KAMITANI, Yasuyuki FUJIYA, Masahiko TOYODA, Saneyuki GOYA, Toshiya WATANABE

Read full paper
Structural Evolution of Highly Active Multicomponent Catalysts for Selective Propylene Oxidation

Structural Evolution of Highly Active Multicomponent Catalysts for Selective Propylene Oxidation

Multicomponent Bi-Mo-Fe-Co oxide catalysts prepared via flame spray pyrolysis were tested for selective propylene oxidation, showing high conversion (>70%) and selectivity (>85%) for acrolein and acrylic acid at temperatures of 330 ◦C. During extended time-on-stream tests (5–7 days), the catalysts retained high activity while undergoing diverse structural changes. This was evident on: (a) the atomic scale, using powder X-ray diffraction, Raman spectroscopy, X-ray absorption spectros... Read more

Paul Sprenger, Thomas L Sheppard, Jussi-Petteri Suuronen, Abhijeet Gaur, Federico Benzi and Jan-Dierk Grunwaldt

Read full paper
Allometry and integration do not strongly constrain beak shape evolution in large-billed (Corvus macrorhynchos) and carrion crows (Corvus corone)

Allometry and integration do not strongly constrain beak shape evolution in large-billed (Corvus macrorhynchos) and carrion crows (Corvus corone)

Here, to evaluate the intensity of evolutionary constraints on avian beak shape more appropriately, we selected large billed (Corvus macrorhynchos) and carrion crows (Corvus corone) as study objects. These landbird species seem to experience selection pressures favoring a departure from an allometric trajectory. A landmark based geometric morphometric approach using three dimensional reconstructions of CT scan images revealed that only 45.4% of the total shape variation was explained by allom... Read more

Takeshi Yamasaki, Sou Aoki, Masayoshi Tokita

Read full paper
Partial dissolution of carbonate rock grains during reactive CO2-saturated brine injection under reservoir conditions

Partial dissolution of carbonate rock grains during reactive CO2-saturated brine injection under reservoir conditions

Our novel procedure of injecting oil after reactive transport has revealed previously unidentified (ghost) regions of partially-dissolved grains of carbonate rock. X-ray micro-tomography and FIB-SEM techniques were used to identify and resolve these ghost regions in three-dimensions at the nm- to µm-scale. Considering the solid part of the ghost regions as macro (bulk) pore space can result in the overestimation of porosity and permeability predi... Read more

Kamaljit Singh , Benaiah U. Anabaraonye , Martin J. Blunt , John Crawshaw

Read full paper
Operative Anatomy of the Human Skull: A Virtual Reality Expedition

Operative Anatomy of the Human Skull: A Virtual Reality Expedition

The human cranial vault possesses an incredible, complex anatomical intricacy. Bridging the divide between 2-dimensional (2D) learning resources and the 3-dimensional (3D) world in which the anatomy becomes clinically relevant poses an intellectual challenge. Advances in computer graphics and modelling technologies have allowed increasingly accurate and representative resources to supplement cadaveric dissection specimens. To create accurate v... Read more

Benjamin K Hendricks, MD Akash J Patel, MD Jerome Hartman Mark F Seifert, PhD Aaron Cohen-Gadol, MD, MSc, MBA

Read full paper
Metal-Organic Framework Crystal-Glass Composites

Metal-Organic Framework Crystal-Glass Composites

The majority of research into metal-organic frameworks (MOFs) focuses on their crystalline nature. However, in recent research the vitrification of a number of MOFs has been revealed. We propose that the solid-liquid phase transitions involved in MOF-glass formation can provide unique opportunities for the creation of a new class of functional, stable and porous composite materials. Described herein is the design, synthesis, and characterisation of novel metal-organic framework (MOF) crystal-... Read more

Jingwei Hou, Christopher W. Ashling, Sean M. Collins, Andraž Krajnc, Chao Zhou, Louis Longley, Duncan N. Johnstone, Philip A. Chater, Shichun Li, François-Xavier Coudert, David A. Keen, Paul A. Midgley, Gregor Mali, Vicki Chen, Thomas Bennett

Read full paper
Digitizing extant bat diversity: An open-access repository of 3D μCT-scanned skulls for research and education

Digitizing extant bat diversity: An open-access repository of 3D μCT-scanned skulls for research and education

Biological specimens are primary records of organismal ecology and history. As such, museum collections are invaluable repositories for testing ecological and evolutionary hypotheses across the tree of life. Digitizing and broadly sharing the phenotypic data from these collections serves to expand the traditional reach of museums, enabling widespread data sharing, collaboration, and education at an unprecedented scale. In recent years, μCT-scanning has been adopted as one way for efficiently... Read more

Jeff J. Shi, Erin P. Westeen, Daniel L. Rabosky

Read full paper
3D cephalometric analysis using Magnetic Resonance Imaging: validation of accuracy and reproducibility

3D cephalometric analysis using Magnetic Resonance Imaging: validation of accuracy and reproducibility

The aim of this study was to validate geometric accuracy and in vivo reproducibility of landmark-based cephalometric measurements using high-resolution 3D Magnetic Resonance Imaging (MRI) at 3 Tesla. (…) In conclusion, this study demonstrates that accurate and reproducible 3D cephalometric analysis can be performed without exposure to ionizing radiation using MRI.

Read more

Alexander Juerchott, Muhammad Abdullah Saleem, Tim Hilgenfeld, Christian Freudlsperger, Sebastian Zingler, Christopher J. Lux, Martin Bendszus & Sabine Heiland

Read full paper
Simulation Analysis on Water’s Micro Seepage Laws under Different Pressure Gradients Using Computed Tomography Method

Simulation Analysis on Water’s Micro Seepage Laws under Different Pressure Gradients Using Computed Tomography Method

The aim of this paper was to develop a model that can characterize the actual micropore structures in coal and gain an in-depth insight into water’s seepage rules in coal pores under different pressure gradients from a microscopic perspective. To achieve this goal, long-flame coals were first scanned by an X-ray 3D microscope; then, through a representative elementary volume (REV) analysis, the optimal side length was determined to be 60 μm; subsequently, by using Avizo software, the coal ... Read more

Gang Zhou, Lei Qiu, Wenzheng Zhang, and Jiao Xue

Read full paper
Estimating the Effective Elastic Parameters of Nodular Cast Iron from Micro-Tomographic Imaging and Multiscale Finite Elements: Comparison between Numerical and Experimental Results

Estimating the Effective Elastic Parameters of Nodular Cast Iron from Micro-Tomographic Imaging and Multiscale Finite Elements: Comparison between Numerical and Experimental Results

We describe in detail a methodology to estimate the effective elastic parameters of nodular cast iron, using micro-tomography in conjunction with multiscale finite elements. We discuss the adjustment of the image acquisition parameters, address the issue of the representative-volume choice, and present a brief discussion on image segmentation. In addition, the finite-element computational implementation developed to estimate the effective elastic parameters from segmented microstructural imag... Read more

Andre Pereira, Marcio Costa, Carla Anflor, Juan Pardal and Ricardo Leiderman

Read full paper
Tomographic investigation of the effects of second phases on the biodegradation and nano-mechanical performance of a Mg-Zn-Ca alloy

Tomographic investigation of the effects of second phases on the biodegradation and nano-mechanical performance of a Mg-Zn-Ca alloy

A combination of 3D tomography techniques provides direct evidence that links the phase assemblage to the bio-corrosion behaviour of a magnesium-zinc-calcium (Mg-Zn-Ca) alloy. The true shape, connectivity and volume fraction of the components have been determined using focused ion beam (FIB) tomography. The mechanism of the effect of the components with different morphologies on biodegradation was studied with the help of FIB. Micro X-ray CT (MicroCT) was used to investigate the degradation o... Read more

Y.Lu, R.G.Ding, Y.L.Chiu, I.P.Jones

Read full paper