Welcome to the Amira-Avizo Software Use Case Gallery
Below you will find a collection of use cases of our 3D data visualization and analysis software. These use cases include scientific publications, articles, papers, posters, presentations or even videos that show how Amira-Avizo Software is used to address various scientific and industrial research topics.
Use the Domain selector to filter by main application area, and use the Search box to enter keywords related to specific topics you are interested in.
The most common means of fabricating membrane electrode assemblies (MEAs) for polymer electrolyte fuel cells (PEFCs) involves a hot-press step. The conditions used to perform the hot-press impacts the performance and durability of the fuel cell.
However, the hot-press process is not essential for achieving operational MEAs and some practitioners dispense with the hot-press stage altogether by using a self-assembled approach. By performing the integration of the components in-situ durin... Read more
Jennifer Hack, T. M. M. Heenan, F. Iacoviello, N. Mansor, Q. Meyer, P. Shearing, N. Brandon and D. J. L. Brett
3D Failure Analysis of Pure Mechanical and Pure Chemical Degradation in Fuel Cell Membranes
Lifetime-limiting failure of fuel cell membranes is generally attributed to their chemical and/or mechanical degradation. Although both of these degradation modes occur concurrently during operational duty cycles, their uncoupled investigations can provide useful insights into their individual characteristics and consequential impacts on the overall membrane failure.
X-ray computed tomography is emerging as an advantageous tool for fuel cell failure analysis due to its non-destructive ... Read more
Yadvinder Singh, Francesco P. Orfino, Monica Dutta, and Erik Kjeang
Quantification of the degradation of Ni-YSZ anodes upon redox cycling
Ni-YSZ anodes for Solid Oxide Fuel Cells are vulnerable to microstructural damage during redox cycling leading to a decrease in the electrochemical performance.
- Quantification of redox damage by coupling 3D tomography, EIS and nanoindentation.
- YSZ fracture, Ni detachment and agglomeration led to irreversible mechanical damage.
- Ni nanoparticles obtained upon redox cycling improve electrochemical performance.
- Loss in TPB densi... Read more
Bowen Song, Enrique Ruiz-Trejo, Antonio Bertei, Nigel P.Brandon
Cellular in vivo 3D imaging of the cornea by confocal laser scanning microscopy
We present an in vivo confocal laser scanning microscopy based method for large 3D reconstruction of the cornea on a cellular level with cropped volume sizes up to 266 x 286x 396 µm3.
The microscope objective used is equipped with a piezo actuator for automated, fast and precise closed-loop focal plane control. Furthermore, we present a novel concave surface contact cap, which significantly reduces eye movements by up to 87%, hence increasing the overlapping image area of the whole st... Read more
Sebastian Bohn, Karsten Sperlich, Stephan Allgeier, Andreas Bartschat, Ruby Prakasam, Klaus-martin Reichert, Heinrich Stolz, Rudolf Guthoff, Ralf Mikut, Bernd Köhler, and Oliver Stachs
Chronic cigarette smoke exposure drives spiral ganglion neuron loss in mice
Tobacco use is associated with an increased risk of hearing loss in older individuals, suggesting cigarette smoke (CS) exposure may target the peripheral auditory organs. However, the effects of CS exposure on general cochlear anatomy have not previously been explored.
Here we compare control and chronic CS exposed cochleae from adult mice to assess changes in structure and cell survival. Two-photon imaging techniques, including the imaging of second harmonic generation (SHG) and two-p... Read more
Stephen T. Paquette, Ryan P. Dawes, Isaac K. Sundar, Irfan Rahman, Edward B. Brown & Patricia M. White
Our parametric study shows that increasing the porosity in the spongy layer beyond 10% enhances the effective transport parameters of the spongy layer at an exponential rate, but linearly for the full anode. For the first time, local and global mass transport properties are correlated to the microstructure, which is of wide interest for rationalizing the design optimization of SOFC electrodes and more generally for hierarchical materials in batteries and membranes.
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Xuekun Lu, Oluwadamilola O. Taiwo, Antonio Bertei, Tao Li, Kang Li, Dan J.L. Brett, Paul R.Shearing
Durable and self-hydrating tungsten carbide-based composite polymer electrolyte membrane fuel cells
Proton conductivity of the polymer electrolyte membranes in fuel cells dictates their performance and requires sufficient water management. Here, we report a simple, scalable method to produce well-dispersed transition metal carbide nanoparticles. We demonstrate that these, when added as an additive to the proton exchange Nafion membrane, provide significant enhancement in power density and durability over 100 hours, surpassing both the baseline Nafion and platinum-containing recast Nafion ... Read more
Weiqing Zheng, Liang Wang, Fei Deng, Stephen A. Giles, Ajay K. Prasad, Suresh G. Advani, Yushan Yan & Dionisios G. Vlachos
In this study, a series of alumina hollow fibers have been prepared with varied polymer binder (polyethersulfone, PESf) concentration and new polymer-based internal coagulant (aqueous solution of polyvinyl alcohol, PVA). For the first time, the micro-channels were characterized in 3D using X-ray CT to determine micro-channel densities and diameters in the radial direction, as well as the 2D measurement of the pore size in the sponge-like layer.
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Tao Li, Xuekun Lu, Bo Wang, Zhentao Wu, Kang Li, Dan J.L. Brett, Paul R. Shearing
Contrast-enhanced 3D micro-CT of plant tissues using different impregnation techniques
X-ray micro-CT has increasingly been used for 3D imaging of plant structures. At the micrometer reso-lution however, limitations in X-ray contrast often lead to datasets with poor qualitative and quantitative measures, especially within dense cell clusters of plant tissue specimens. The current study developed protocols for delivering a cesium based contrast enhancing solution to varying plant tissue specimens for the purpose of improving 3D tissue structure characterization within plant spec... Read more
Zi Wang, Pieter Verboven and Bart Nicolai, Department of Biosystems KU Leuven – University of Leuven Willem de Croylaan, Leuven Belgium
Root-knot nematodes induce galls that contain giant-feeding cells harboring multiple enlarged nuclei within the roots of host plants. It is recognized that the cell cycle plays an essential role in the set-up of a peculiar nuclear organization that seemingly steers nematode feeding site induction and development. Functional studies of a large set of cell cycle genes in transgenic lines of the model host Arabidopsis thaliana have contributed to better understand the role of the cell cycle comp... Read more
Antonino de Souza Junior José Dijair, Pierre Olivier, Coelho Roberta R., Grossi-de-Sa Maria F., Engler Gilbert, de Almeida Engler Janice / Institut National de la Recherche Agronomique, Université Côte d’Azur, Centre National de la Recherche Scientifique, Institut Sophia Agrobiotech, Sophia-Antipolis, France
Despite the progress made in selective plane illumination microscopy, high-resolution 3D live imaging of multicellular specimens remains challenging. Tiling light-sheet selective plane illumination microscopy (TLS-SPIM) with real-time light-sheet optimization was developed to respond to the challenge…
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Qinyi Fu, Benjamin L. Martin, David Q. Matus, Liang Gao
Noise induced hearing loss (NIHL) is a disease that affects millions of Americans. Identifying genetic pathways that influence recovery from noise exposure is an important step forward in understanding NIHL. The transcription factor Foxo3 integrates the cellular response to oxidative stress and plays a role in extending lifespan in many organisms, including humans. Here we show that Foxo3 is required for auditory function after noise exposure in a mouse model system, measured by ABR…Read more
Felicia Gilels, Stephen T. Paquette, Holly J. Beaulac, Anwen Bullen & Patricia M. White
This paper demonstrates for the first time down-regulation of the endogenous nuclear retained mutant DMPK mRNAs targeted with lentivirus-delivered short hairpin RNAs (shRNAs). This nuclear RNAi(-like) phenomenon was not observed when synthetic siRNAs were delivered by cationic lipids, suggesting either a link between processing of the shRNA and nuclear import or a separate pathway for processing shRNAs in the nuclei.
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Marc-André Langlois, Christelle Boniface, Gang Wang, Jessica Alluin, Paul M. Salvaterra, Jack Puymirat, John J. Rossi, Nan Sook Lee