Welcome to the Amira-Avizo Software Use Case Gallery

Below you will find a collection of use cases of our 3D data visualization and analysis software. These use cases include scientific publications, articles, papers, posters, presentations or even videos that show how Amira-Avizo Software is used to address various scientific and industrial research topics.

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A high-throughput, fully automated morphometric method to discover the genes controlling shape differences in the Faroese mice

A high-throughput, fully automated morphometric method to discover the genes controlling shape differences in the Faroese mice

The Faroe Islands are a group of islands in the North Atlantic that are known for its natural beauty, Viking culture and a special population of house mouse. The Faroese house mouse from the most remote island of the Faroese, Mykines (population: 10 people), looked so distinct when it was discovered that it was declared a subspecies, Mus musculus faeroenesis. These mice are large-bodied and showed an extreme form of left-right asymmetry in its skull. Our research group has... Read more

Yingguang Frank Chan, William H. Beluch, Rémi Blanc

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Ptychographic X-ray CT characterization of the osteocyte lacuno-canalicular network in a male rat's glucocorticoid induced osteoporosis model

Ptychographic X-ray CT characterization of the osteocyte lacuno-canalicular network in a male rat's glucocorticoid induced osteoporosis model

Ptychographic X-ray computed tomography (PXCT) is a quantitative imaging modality that non-destructively maps the 3D electron density inside an object with tens of nanometers spatial resolution. This method provides unique access to the morphology and structure of the osteocyte lacuno-canalicular network (LCN) and nanoscale density of the tissue in the vicinity of an osteocyte lacuna.  Our findings indicate that PXCT can non-destructively provide detailed, nanoscale information on the 3D org... Read more

Antonia Ciani, Hechmi Toumi, Stéphane Pallu, Esther H.R.Tsai, Ana Diaz, Manuel Guizar-Sicairos, Mirko Holler, Eric Lespessailles, Cameron M.Kewish | Synchrotron Soleil, France

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Morphology of the bryozoan Cinctipora elegans (Cyclostomata, Cinctiporidae) with first data on its sexual reproduction and the cyclostome neuro-muscular system

Morphology of the bryozoan Cinctipora elegans (Cyclostomata, Cinctiporidae) with first data on its sexual reproduction and the cyclostome neuro-muscular system

Cyclostome bryozoans are an ancient group of marine colonial suspension-feeders comprising approximately 700 extant species. Previous morphological studies are mainly restricted to skeletal characters whereas data on soft tissues obtained by state-of-the-art methods are still lacking. In order to contribute to issues related to cyclostome ground pattern reconstruction, we analyzed the morphology of the neuromuscular system Cinctipora elegans by means of immunocytochemical staining,... Read more

Thomas F. Schwaha, Stephan Handschuh, Andrew N. Ostrovsky, Andreas Wanninger

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Secure corridor for infraacetabular screws in acetabular fracture fixation—a 3-D radiomorphometric analysis of 124 pelvic CT datasets

Secure corridor for infraacetabular screws in acetabular fracture fixation—a 3-D radiomorphometric analysis of 124 pelvic CT datasets

Acetabular fracture surgery is directed toward anatomical reduction and stable fixation to allow for the early functional rehabilitation of an injured hip joint. Recent biomechanical investigations have shown the superiority of using an additional screw in the infraacetabular (IA) region, thereby transfixing the separated columns to strengthen the construct by closing the periacetabular fixation frame. However, the inter-individual existence and variance concerning secure IA screw corridors a... Read more

Stephan Arlt, Hansrudi Noser, Andreas Wienke, Florian Radetzki, Gunther Olaf Hofmann, Thomas Mendel

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Three-dimensional virtual histology of human cerebellum by X-ray phase-contrast tomography

Three-dimensional virtual histology of human cerebellum by X-ray phase-contrast tomography

To quantitatively evaluate brain tissue and its corresponding function, knowledge of the 3D cellular distribution is essential. The gold standard to obtain this information is histology, a destructive and labor-intensive technique where the specimen is sliced and examined under a light microscope, providing 3D information at nonisotropic resolution. To overcome the limitations of conventional histology, we use phase-contrast X-ray tomography with optimized optics, reconstruction, and image an... Read more

Mareike Töpperwien, Franziska van der Meer, Christine Stadelmann, and Tim Salditt

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In-situ, time resolved monitoring of uranium in BFS:OPC grout. Part 2: Corrosion in water

In-situ, time resolved monitoring of uranium in BFS:OPC grout. Part 2: Corrosion in water

To reflect potential conditions in a geological disposal facility, uranium was encapsulated in grout and submersed in de-ionised water for time periods between 2–47 weeks. Synchrotron X-ray Powder Diffraction and X-ray Tomography were used to identify the dominant corrosion products and measure their dimensions. Uranium dioxide was observed as the dominant corrosion product and time dependent thickness measurements were used to calculate oxidation rates. The effectiveness of physical and ch... Read more

C. A. Stitt, C. Paraskevoulakos, A. Banos, N. J. Harker, K. R. Hallam, H. Pullin, A. Davenport, S. Street, T. B. Scott

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Resurrecting Darwin’s Niata - anatomical, biomechanical, genetic, and morphometric studies of morphological novelty in cattle

Resurrecting Darwin’s Niata - anatomical, biomechanical, genetic, and morphometric studies of morphological novelty in cattle

The Niata was a cattle variety from South America that figured prominently in writings on evolution by Charles Darwin. Its shortened head and other aspects of its unusual morphology have been subject of unsettled discussions since Darwin’s time. Here, we examine the anatomy, cranial shape, skull biomechanics, and population genetics of the Niata. Our results show that the Niata was a viable variety of cattle and exhibited anatomical differences to known chondrodysplastic forms. In cranial s... Read more

Kristof Veitschegger, Laura A. B. Wilson, Beatrice Nussberger, Glauco Camenisch, Lukas F. Keller, Stephen Wroe, Marcelo R. Sánchez-Villagra

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Understanding the near-threshold crack growth behavior in an aluminum alloy by x-ray tomography

Understanding the near-threshold crack growth behavior in an aluminum alloy by x-ray tomography

The near-threshold behavior of long cracks is evaluated using pre-cracked flat dogbone specimens of a commercial aluminum alloy in two heat treatment states. Once the threshold was known, the crack initially introduced by cyclic compression was propagated under load control with approximately
constant range of the stress intensity factor at values close to the threshold values. The 3D morphology of the crack and the spatial distribution of the primary precipitates obtained by µ-CT were... Read more

Marcel Wicke, Angelika Brueckner-Foit, Tina Kirsten, Martina Zimmermann, Fatih Buelbuel, Hans-Juergen Christ

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3D characterization of the fracture mechanisms of a Fe-rich Al-Si-Cu alloy

3D characterization of the fracture mechanisms of a Fe-rich Al-Si-Cu alloy

The effect of the defect size and morphology on the fatigue damage evolution was analysed in a recycled Al-Si-Cu alloy by micro-computed tomography and scanning electron microscopy. Fatigue tests were performed and the different crack initiation scenarios were characterized and classified. The interaction between shrinkage and gas pores was the key crack initiation mechanism and the ß-Al5FeSi particles did not play any role in the crack initiation phase. However, crack path analysis indicate... Read more

Angelika Brueckner-Foit, Inigo Bacaicoa, Martin Luetje, Marcel Wicke, Andreas Geisert, Martin Fehlbier

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Characterisation of the diffusion properties of metal foam hybrid flow-fields for fuel cells using optical flow visualisation and X-ray computed tomography

Characterisation of the diffusion properties of metal foam hybrid flow-fields for fuel cells using optical flow visualisation and X-ray computed tomography

The flow distribution behaviour of open-cell metallic foam fuel cell flow-fields are evaluated using ex-situ optical analysis and X-ray computed tomography (X-ray CT). Five different manifold designs are evaluated and flow distribution and pressure drop ... Read more

A.Fly, D.Butcher, Q.Meyer, M.Whiteley, A.Spencer, C.Kim, P.R.Shearing, D.J.L.Brett, R.Chen

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An Investigation of Fiber Reinforced Chemically Bonded Phosphate Ceramic Composites at Room Temperature

An Investigation of Fiber Reinforced Chemically Bonded Phosphate Ceramic Composites at Room Temperature

In this study, chemically bonded phosphate ceramic (CBPC) fiber reinforced composites were made at indoor temperatures. The mechanical properties and microstructure of the CBPC composites were studied. The CBPC matrix of aluminum phosphate binder, metakaolin, and magnesia with different Si/P ratios was prepared. The results show that when the Si/P ratio was 1.2, and magnesia content in the CBPC was 15%, CBPC reached its maximum flexural strength. The fiber reinforced CBPC composites were prep... Read more

Zhu Ding; Yu-Yu Li; Can Lu; Jian Liu

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Mechanical adaptation of trabecular bone morphology in the mammalian mandible

Mechanical adaptation of trabecular bone morphology in the mammalian mandible

Alveolar bone, together with the underlying trabecular bone, fulfils an important role in providing structural support against masticatory forces. Diseases such as osteoporosis or periodontitis cause alveolar bone resorption which weakens this structural support and is a major cause of tooth loss. However, the functional relationship between alveolar bone remodelling within the molar region and masticatory forces is not well understood. This study investigated this relationship by comparing m... Read more

Peter J. Watson, Laura C. Fitton, Carlo Meloro, Michael J. Fagan, Flora Gröning

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The morphological diversity of Garra barreimiae

The morphological diversity of Garra barreimiae

Garra barreimiae (Fowler and Steinitz, Bull Res Counc Isr 5B:262–289, 1956) is a freshwater fish that lives throughout the Hajar Mountains of Oman and the United Arab Emirates. Previously, four different genetic clades (West clade, C... Read more

Arthur Pichler; Harald Ahnelt; Sandra Kirchner; Helmut Sattmann; Elisabeth Haring; Stephan Handschuh; Jörg Freyhof; Reginald Victor; Luise Kruckenhauser

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X-ray Tomographic Imaging of Tensile Deformation Modes of Electrospun Biodegradable Polyester Fibers

X-ray Tomographic Imaging of Tensile Deformation Modes of Electrospun Biodegradable Polyester Fibers

Electrospun constructs for the repair of load-bearing tissues are required to have adequate mechanical properties. However, the failure mechanisms of electrospun fibrous materials are not well understood. Existing literature focuses on failure modes of individual fibers and/or on bulk mechanical properties of whole fiber mats.

Electrospinning allows the production of fibrous networks for tissue engineering, drug delivery, and wound healing in health care. It enables the production of c... Read more

Jekaterina Maksimcuka; Akiko Obata ; William W. Sampson ; Remi Blanc ; Chunxia Gao ; Philip J. Withers ; Olga Tsigkou ; Toshihiro Kasuga ; Peter D. Lee ; Gowsihan Poologasundarampillai

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Evolution of damage during the fatigue of 3D woven glass-fibre reinforced composites subjected to tension–tension loading observed by time-lapse X-ray tomography

Evolution of damage during the fatigue of 3D woven glass-fibre reinforced composites subjected to tension–tension loading observed by time-lapse X-ray tomography

Three dimensional (3D) composites were proposed over 40 years ago in an attempt to overcome the shortcomings of 2D laminates, by incorporating fibres into the through-thickness direction. 3D weaving offer significant manufacturing benefits as well as creating versatile textiles having a range of 3D architectures.

The development of fatigue damage in a glass fibre modified layer-to-layer three dimensional (3D) woven composite has been followed by time-lapse X-ray computed tomograp... Read more

B. Yu, R. Blanc, C. Soutis, P.J. Withers

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Investigation of Carbon Fiber Architecture in Braided Composites Using X-Ray CT Inspection

Investigation of Carbon Fiber Architecture in Braided Composites Using X-Ray CT Inspection

During the fabrication of braided carbon fiber composite materials, process variations occur which affect the fiber architecture.

Quantitative measurements of local and global fiber architecture variations are needed to determine the potential effect of process variations on mechanical properties of the cured composite. Although non-destructive inspection via X-ray CT imaging is a promising approach, difficulties in quantitative analysis of the data arise due to the similar densities o... Read more

Daniel J. Rhoads, Sandi G. Miller, Gary D. Roberts, Richard W. Rauser, Dmitry Golovaty, J. Patrick Wilber, Malena I. Español

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Synchrotron X-ray tomographic quantification of microstructural evolution in ice cream – a multi-phase soft solid

Synchrotron X-ray tomographic quantification of microstructural evolution in ice cream – a multi-phase soft solid

The microstructure of food affects our sensorial perception, its attractiveness, and the manufactured product’s shelf-life.

Microstructural evolution in soft matter directly influences not only the material’s mechanical and functional properties, but also our perception of that material’s taste. Using synchrotron X-ray tomography and cryo-SEM we investigated the time–temperature evolution of ice cream’s microstructure. This was enabled via three adv... Read more

Enyu Guo, Guang Zeng, Daniil Kazantsev, Peter Rockett, Julian Bent, Mark Kirkland, Gerard Van Dalen, David S. Eastwood, David StJohn and Peter D. Lee

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In situ studies of materials for high temperature CO2 capture and storage

In situ studies of materials for high temperature CO2 capture and storage

Carbon capture and storage (CCS) offers a possible solution to curb the CO2 emissions from stationary sources in the coming decades, considering the delays in shifting energy generation to carbon neutral sources such as wind, solar and biomass.

The most mature technology for post-combustion capture uses a liquid sorbent, amine scrubbing. However, with the existing technology, a large amount of heat is required for the regeneration of the liquid sorbent, which... Read more

Matthew T. Dunstan, Serena A. Maugeri, Wen Liu, Matthew G. Tucker, Oluwadamilola O. Taiwo, Belen Gonzalez, Phoebe K. Allan, Michael W. Gaultois, Paul R. Shearing, David A. Keen, Anthony E. Phillips, Martin T. Dove, Stuart A. Scott, John S. Dennish and Clare P. Grey

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Correlation between triple phase boundary and the microstructure of Solid Oxide Fuel Cell anodes

Correlation between triple phase boundary and the microstructure of Solid Oxide Fuel Cell anodes

This study aims to correlate the active triple phase boundaries (TPBs) to the variation of as-prepared anode microstructures and Ni densifications based on the reconstructed 3D volume of an SOFC anode, providing a point of comparison with theoretical studies that reveal the relationship of TPBs and the material microstructure using randomly packed spheres models.

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Xuekun Lu, Thomas M.M. Heenan, Josh J. Bailey, Tao Li, Kang Li, Daniel J.L. Brett, Paul R. Shearing, Electrochemical Innovation Lab, Department of Chemical Engineering, University College London, London

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New Method for the Deposition of Nickel Oxide in Porous Scaffolds for Electrodes in Solid Oxide Fuel Cells and Electrolyzers

New Method for the Deposition of Nickel Oxide in Porous Scaffolds for Electrodes in Solid Oxide Fuel Cells and Electrolyzers

A simple chemical bath deposition is used to coat a complex porous ceramic scaffold with a conformal Ni layer.

The resulting composite is used as a solid oxide fuel cell electrode, and its electrochemical response is measured in humidified hydrogen. X‐ray tomography is used to determine the microstructural characteristics of the uncoated and Ni‐coated porous structure, which include the surface area to total volume, the radial pore size, and the size of the necks between the pores.... Read more

Dr. Enrique Ruiz‐Trejo, Milla Puolamaa, Brian Sum, Dr. Farid Tariq, Dr. Vladimir Yufit, Prof. Nigel P. Brandon

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Analyzing the effects of powder and post-processing on porosity and properties of electron beam melted Ti-6Al-4V

Analyzing the effects of powder and post-processing on porosity and properties of electron beam melted Ti-6Al-4V

Metal additive manufacturing techniques such as the powder-bed systems are developing as a novel method for producing complex components.

This study uses synchrotron-based X-ray microtomography to investigate porosity in electron beam melted Ti-6Al-4V in the as-built and post-processed state for two different powders. The presence of gas porosity in the starting powder was shown to correlate to porosity in the as-built components. This porosity was observed to shrink after a hot isosta... Read more

Ross Cunningham, Andrea Nicolas, John Madsen, Eric Fodran, Elias Anagnostou, Michael D. Sangid & Anthony D. Rollett

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