Welcome to the Amira-Avizo Software Use Case Gallery

Below you will find a collection of use cases of our 3D data visualization and analysis software. These use cases include scientific publications, articles, papers, posters, presentations or even videos that show how Amira-Avizo Software is used to address various scientific and industrial research topics.

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Resurrecting Darwin’s Niata - anatomical, biomechanical, genetic, and morphometric studies of morphological novelty in cattle

Resurrecting Darwin’s Niata - anatomical, biomechanical, genetic, and morphometric studies of morphological novelty in cattle

The Niata was a cattle variety from South America that figured prominently in writings on evolution by Charles Darwin. Its shortened head and other aspects of its unusual morphology have been subject of unsettled discussions since Darwin’s time. Here, we examine the anatomy, cranial shape, skull biomechanics, and population genetics of the Niata. Our results show that the Niata was a viable variety of cattle and exhibited anatomical differences to known chondrodysplastic forms. In cranial s... Read more

Kristof Veitschegger, Laura A. B. Wilson, Beatrice Nussberger, Glauco Camenisch, Lukas F. Keller, Stephen Wroe, Marcelo R. Sánchez-Villagra

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3D characterization of the fracture mechanisms of a Fe-rich Al-Si-Cu alloy

3D characterization of the fracture mechanisms of a Fe-rich Al-Si-Cu alloy

The effect of the defect size and morphology on the fatigue damage evolution was analysed in a recycled Al-Si-Cu alloy by micro-computed tomography and scanning electron microscopy. Fatigue tests were performed and the different crack initiation scenarios were characterized and classified. The interaction between shrinkage and gas pores was the key crack initiation mechanism and the ß-Al5FeSi particles did not play any role in the crack initiation phase. However, crack path analysis indicate... Read more

Angelika Brueckner-Foit, Inigo Bacaicoa, Martin Luetje, Marcel Wicke, Andreas Geisert, Martin Fehlbier

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Mechanical adaptation of trabecular bone morphology in the mammalian mandible

Mechanical adaptation of trabecular bone morphology in the mammalian mandible

Alveolar bone, together with the underlying trabecular bone, fulfils an important role in providing structural support against masticatory forces. Diseases such as osteoporosis or periodontitis cause alveolar bone resorption which weakens this structural support and is a major cause of tooth loss. However, the functional relationship between alveolar bone remodelling within the molar region and masticatory forces is not well understood. This study investigated this relationship by comparing m... Read more

Peter J. Watson, Laura C. Fitton, Carlo Meloro, Michael J. Fagan, Flora Gröning

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3D Reconstruction of Lipid Droplets in the Seed of Brassica napus

3D Reconstruction of Lipid Droplets in the Seed of Brassica napus

Rapeseed is one of the most important and widely cultured oilseed crops for food and nonfood purposes worldwide. Neutral lipids are stored in lipid droplets (LDs) as fuel for germination and subsequent seedling growth. Most of the LD detection in seeds was still in 2D levels, and some of the details might have been lost in previous studies. In the present work, the configuration of LDs in seeds was obtained by confocal imaging combined with 3D reconstruction technology in Brassica napus<... Read more

Yongtai Yin, Liangxing Guo, Kang Chen, Zhenyi Guo, Hongbo Chao, Baoshan Wang, and Maoteng Licorresponding author

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The morphological diversity of Garra barreimiae

The morphological diversity of Garra barreimiae

Garra barreimiae (Fowler and Steinitz, Bull Res Counc Isr 5B:262–289, 1956) is a freshwater fish that lives throughout the Hajar Mountains of Oman and the United Arab Emirates. Previously, four different genetic clades (West clade, C... Read more

Arthur Pichler; Harald Ahnelt; Sandra Kirchner; Helmut Sattmann; Elisabeth Haring; Stephan Handschuh; Jörg Freyhof; Reginald Victor; Luise Kruckenhauser

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4D multi-scale imaging of reactive flow in carbonates: Assessing the impact of heterogeneity on dissolution regimes using streamlines at multiple length scales

4D multi-scale imaging of reactive flow in carbonates: Assessing the impact of heterogeneity on dissolution regimes using streamlines at multiple length scales

We have experimentally investigated the impact of heterogeneity on the dissolution of two limestones, characterised by distinct degrees of flow heterogeneity at both the pore and core scales. The two rocks were reacted with reservoir-condition CO2-saturated brine at both scales and scanned dynamically during dissolution. First, 1 cm long 4 mm... Read more

Menke H.P; Reynolds C.A.; Andrew M.G.; Pereira Nunes J.P.; Bijeljic B; Blunt M.J.

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Evolution of damage during the fatigue of 3D woven glass-fibre reinforced composites subjected to tension–tension loading observed by time-lapse X-ray tomography

Evolution of damage during the fatigue of 3D woven glass-fibre reinforced composites subjected to tension–tension loading observed by time-lapse X-ray tomography

Three dimensional (3D) composites were proposed over 40 years ago in an attempt to overcome the shortcomings of 2D laminates, by incorporating fibres into the through-thickness direction. 3D weaving offer significant manufacturing benefits as well as creating versatile textiles having a range of 3D architectures.

The development of fatigue damage in a glass fibre modified layer-to-layer three dimensional (3D) woven composite has been followed by time-lapse X-ray computed tomograp... Read more

B. Yu, R. Blanc, C. Soutis, P.J. Withers

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New Method for the Deposition of Nickel Oxide in Porous Scaffolds for Electrodes in Solid Oxide Fuel Cells and Electrolyzers

New Method for the Deposition of Nickel Oxide in Porous Scaffolds for Electrodes in Solid Oxide Fuel Cells and Electrolyzers

A simple chemical bath deposition is used to coat a complex porous ceramic scaffold with a conformal Ni layer.

The resulting composite is used as a solid oxide fuel cell electrode, and its electrochemical response is measured in humidified hydrogen. X‐ray tomography is used to determine the microstructural characteristics of the uncoated and Ni‐coated porous structure, which include the surface area to total volume, the radial pore size, and the size of the necks between the pores.... Read more

Dr. Enrique Ruiz‐Trejo, Milla Puolamaa, Brian Sum, Dr. Farid Tariq, Dr. Vladimir Yufit, Prof. Nigel P. Brandon

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Morphology and ontogeny of Lophopus crystallinus lophophore support the epistome as ancestral character of phylactolaemate bryozoans

Morphology and ontogeny of Lophopus crystallinus lophophore support the epistome as ancestral character of phylactolaemate bryozoans

Phylactolaemate bryozoans are the sister-group to all remaining bryozoan taxa. Consequently, their study is essential to reveal and analyze ancestral traits of Phylactolaemata and Bryozoa in general.

They are the only bryozoans to possess an epistome which traditionally has been regarded as shared with phoronids and brachiopods. Contrary to older observations, an epistome was recently reported to be missing in the early branching phylactolaemate Lophopus crystallinus. In this... Read more

Thomas Schwaha

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Reinvestigating an enigmatic Late Cretaceous monocot: morphology, taxonomy, and biogeography of Viracarpon

Reinvestigating an enigmatic Late Cretaceous monocot: morphology, taxonomy, and biogeography of Viracarpon

Angiosperm-dominated floras of the Late Cretaceous are essential for understanding the evolutionary, ecological, and geographic radiation of flowering plants.

The Late Cretaceous–early Paleogene Deccan Intertrappean Beds of India contain angiosperm-dominated plant fossil assemblages known from multiple localities in central India. Numerous monocots have been documented from these assemblages, providing a window into an important but poorly understood time in their diversification. On... Read more

Kelly K.S. Matsunaga, Selena Y. Smith, Steven R. Manchester, Dashrath Kapgate, Deepak Ramteke, Amin Garbout, and Herminso Villarraga-Gómez

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Cellular in vivo 3D imaging of the cornea by confocal laser scanning microscopy

Cellular in vivo 3D imaging of the cornea by confocal laser scanning microscopy

We present an in vivo confocal laser scanning microscopy based method for large 3D reconstruction of the cornea on a cellular level with cropped volume sizes up to 266 x 286x 396 µm3.

The microscope objective used is equipped with a piezo actuator for automated, fast and precise closed-loop focal plane control. Furthermore, we present a novel concave surface contact cap, which significantly reduces eye movements by up to 87%, hence increasing the overlapping image area of the whole st... Read more

Sebastian Bohn, Karsten Sperlich, Stephan Allgeier, Andreas Bartschat, Ruby Prakasam, Klaus-martin Reichert, Heinrich Stolz, Rudolf Guthoff, Ralf Mikut, Bernd Köhler, and Oliver Stachs

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Chronic cigarette smoke exposure drives spiral ganglion neuron loss in mice

Chronic cigarette smoke exposure drives spiral ganglion neuron loss in mice

Tobacco use is associated with an increased risk of hearing loss in older individuals, suggesting cigarette smoke (CS) exposure may target the peripheral auditory organs. However, the effects of CS exposure on general cochlear anatomy have not previously been explored.

Here we compare control and chronic CS exposed cochleae from adult mice to assess changes in structure and cell survival. Two-photon imaging techniques, including the imaging of second harmonic generation (SHG) and two-p... Read more

Stephen T. Paquette, Ryan P. Dawes, Isaac K. Sundar, Irfan Rahman, Edward B. Brown & Patricia M. White

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Pneumatisation and internal architecture of the Southern Cassowary Casuarius casuarius casque: a microCT study

Pneumatisation and internal architecture of the Southern Cassowary Casuarius casuarius casque: a microCT study

Cranial ornaments such as keratinous horns and bony casques are commonplace amongst birds and take a variety of diverse forms. Possible functions include display, thermoregulation, vocalisation and intraspecific combat, yet few hypotheses have been directly tested. Here we investigate the anatomy and mechanics of the casque of the Southern Cassowary (Casuarius casuarius), and test functional hypotheses using CT-based virtual dissection.

In particular, we determine the nature of pneumat... Read more

Charlotte A. Brassey , Thomas O’Mahoney

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Durable and self-hydrating tungsten carbide-based composite polymer electrolyte membrane fuel cells

Durable and self-hydrating tungsten carbide-based composite polymer electrolyte membrane fuel cells

Proton conductivity of the polymer electrolyte membranes in fuel cells dictates their performance and requires sufficient water management. Here, we report a simple, scalable method to produce well-dispersed transition metal carbide nanoparticles. We demonstrate that these, when added as an additive to the proton exchange Nafion membrane, provide significant enhancement in power density and durability over 100 hours, surpassing both the baseline Nafion and platinum-containing recast Nafion ... Read more

Weiqing Zheng, Liang Wang, Fei Deng, Stephen A. Giles, Ajay K. Prasad, Suresh G. Advani, Yushan Yan & Dionisios G. Vlachos

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A Middle Triassic pachypleurosaur (Diapsida: Eosauropterygia) from a restricted carbonate ramp in the Western Carpathia

A Middle Triassic pachypleurosaur (Diapsida: Eosauropterygia) from a restricted carbonate ramp in the Western Carpathia

An eosauropterygian skeleton found in the Middle Triassic (upper Anisian) Gutenstein Formation of the Fatric Unit (Demänovská dolina Valley, Low Tatra Mountains, Slovakia) represents the earliest known occurrence of marine tetrapods in the Western Carpathians. The specimen represents a partly articulated portion of the postcranial skeleton (nine dorsal vertebrae, coracoid, ribs, gastral ribs, pelvic girdle, femur and one zeugopodial element). It is assigned to the Pachypleurosauria, more pr... Read more

ANDREJ ČERŇANSKÝ, NICOLE KLEIN, JÁN SOTÁK, MÁRIO OLŠAVSKÝ, JURAJ ŠURKA, and PAVEL HERICH

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EM connectomics reveals axonal target variation in a sequence-generating network

EM connectomics reveals axonal target variation in a sequence-generating network

The sequential activation of neurons has been observed in various areas of the brain, but in no case is the underlying network structure well understood. Here we examined the circuit anatomy of zebra finch HVC, a cortical region that generates sequences underlying the temporal progression of the song. We combined serial block-face electron microscopy with light microscopy to determine the cell types targeted by HVC(RA) neurons, which control song timing. Close to their soma, axons... Read more

Jörgen Kornfeld, Sam E Benezra, Rajeevan T Narayanan, Fabian Svara, Robert Egger, Marcel Oberlaender, Winfried Denk, Michael A Long

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Glass fiber length and orientation analysis of reinforced polymers (GFRP)

Glass fiber length and orientation analysis of reinforced polymers (GFRP)

Royal DSM is a global science-based company active in health, nutrition and
materials. Within DSM’s Materials Cluster DSM Engineering Plastics is a global player in specialty plastics. These materials are used in components for the electrical and electronics, automotive, flexible food packaging and consumer goods industries.

A typical product made of DSM Engineering Plastics’ polymer portfolio are USB-C connectors. Key performance indicators for this application are dimension... Read more

Jennifer Schillings, Arno Wilbers and Joachim Loos, DSM Materials Science Center, Geleen, The Netherlands

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AMSC Research, LLC uses Amira software to understand processes and rituals of Egyptian mummification

AMSC Research, LLC uses Amira software to understand processes and rituals of Egyptian mummification

“Scanning is important, but it is really just the first step in an immersive exploration of artifacts” says Elias. Raw data from scans taken of mummies (or other archaeological subject matter) is delivered to AMSC Research as files in a language known as DICOM. Next, these are converted into a visually readable form for analytical purposes and to launch the creative modeling process.

Elias uses Amira software to analyze scan data. Mummies are biological entities, so apart f... Read more

Dr. Jonathan Elias, AMSC Research, LLC

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The Victoria West: earliest prepared core technology in the Acheulean at Canteen Kopje and implications for the cognitive evolution of early hominids

The Victoria West: earliest prepared core technology in the Acheulean at Canteen Kopje and implications for the cognitive evolution of early hominids

Prepared core technology illustrates in-depth planning and the presence of a mental template during the core reduction process. This technology is, therefore, a significant indicator in studying the evolution of abstract thought and the cognitive abilities of hominids. Here, we report on Victoria West cores excavated from the Canteen Kopje site in central South Africa, with a preliminary age estimate of approximately 1 Ma (million years ago) for these cores. Technological analysis shows tha... Read more

Hao Li, Kathleen Kuman, Matt G. Lotter, George M. Leader, Ryan J. Gibbon

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MIA-Clustering: a novel method for segmentation of paleontological material

MIA-Clustering: a novel method for segmentation of paleontological material

Paleontological research increasingly uses high-resolution micro-computed tomography (μCT) to study the inner architecture of modern and fossil bone material to answer important questions regarding vertebrate evolution. This non-destructive method allows for the measurement of otherwise inaccessible morphology. Digital measurement is predicated on the accurate segmentation of modern or fossilized bone from other structures imaged in μCT scans, as errors in segmentation can result in inaccur... Read more

Christopher J. Dunmore​, Gert Wollny, Matthew M. Skinner

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Propagation-based phase-contrast x-ray tomography of cochlea using a compact synchrotron source

Propagation-based phase-contrast x-ray tomography of cochlea using a compact synchrotron source

We demonstrate that phase retrieval and tomographic imaging at the organ level of small animals can be advantageously carried out using the monochromatic radiation emitted by a compact x-ray light source, without further optical elements apart from source and detector. This approach allows to carry out microtomography experiments which – due to the large performance gap with respect to conventional laboratory instruments – so far were usually limited to synchrotron sources. We dem... Read more

Mareike Töpperwien, Regine Gradl, Daniel Keppeler, Malte Vassholz, Alexander Meyer, Roland Hessler, Klaus Achterhold, Bernhard Gleich, Martin Dierolf, Franz Pfeiffer, Tobias Moser & Tim Salditt

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