Welcome to the Amira-Avizo Software Use Case Gallery

Below you will find a collection of use cases of our 3D data visualization and analysis software. These use cases include scientific publications, articles, papers, posters, presentations or even videos that show how Amira-Avizo Software is used to address various scientific and industrial research topics.

Use the Domain selector to filter by main application area, and use the Search box to enter keywords related to specific topics you are interested in.

3D computational anatomy of the scaphoid and its waist for use in fracture treatment

3D computational anatomy of the scaphoid and its waist for use in fracture treatment

A detailed understanding of scaphoid anatomy helps anatomic fracture reduction and optimal screw position. Therefore, we analyzed the size and shape variations of the cartilage and osseous surface, the distribution of volumetric bone mineral density (vBMD), and if the vBMD values differ between a peripheral and a central screw pathway?

Forty-three fresh frozen hand specimens (17 females, 26 males) were analysed with high-resolution peripheral quantitative computed tomography (HR-pQCT) ... Read more

Marc-Daniel Ahrend, Teun Teunis, Hansrudi Noser, Florian Schmidutz, Geoff Richards, Boyko Gueorguiev & Lukas Kamer

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Computational fluid dynamics with imaging of cleared tissue and of in vivo perfusion predicts drug uptake and treatment responses in tumours

Computational fluid dynamics with imaging of cleared tissue and of in vivo perfusion predicts drug uptake and treatment responses in tumours

Understanding the uptake of a drug by diseased tissue, and the drug’s subsequent spatiotemporal distribution, are central factors in the development of effective targeted therapies. However, the interaction between the pathophysiology of diseased tissue and individual therapeutic agents can be complex, and can vary across tissue types and across subjects. Here, we show that the combination of mathematical modelling, high-resolution optical imaging of intact and optically cleared tumour tiss... Read more

Angela d’Esposito, Paul W. Sweeney, Morium Ali, Magdy Saleh, Rajiv Ramasawmy, Thomas A. Roberts, Giulia Agliardi, Adrien Desjardins, Mark F. Lythgoe, R. Barbara Pedley, Rebecca Shipley and Simon Walker-Samuel

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Step-by-step guide to post-acquisition correlation of confocal and FIB/SEM volumes using Amira software

Step-by-step guide to post-acquisition correlation of confocal and FIB/SEM volumes using Amira software

In recent years new methodologies and workflow pipelines for acquiring correlated fluorescence microscopy and volume electron microscopy datasets have been extensively described and made accessible to users of different levels. Post-acquisition image processing, and particularly correlation of the optical and electron data in a single integrated three-dimensional framework can be key for extracting valuable information, especially when imaging large sample volumes such as whole cells or tissu... Read more

Allon Weiner

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Multiscale Co‐reconstruction of Lung Architectures and Inhalable Materials Spatial Distribution

Multiscale Co‐reconstruction of Lung Architectures and Inhalable Materials Spatial Distribution

Pulmonary diseases, such as chronic obstructive pulmonary diseases, lower respiratory infections, and lung cancer are listed in the top ten causes of deaths globally with more than 10 million mortality per year. Apart from oral administration, the Dry Powder Inhalation (DPI) for pulmonary administration provides an important alternative route for targeted treatment of these pulmonary diseases. […] Furthermore, there is a growing demand on und... Read more

Xian Sun, Xiaochuan Zhang, Xiaohong Ren, Hongyu Sun, Li Wu, Caifen Wang, Xiaohui Ye, Peter York, Zhaobing Gao, Hualiang Jiang, Jiwen Zhang, Xianzhen Yin

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Towards digital metal additive manufacturing via high-temperature drop-on-demand jetting

Towards digital metal additive manufacturing via high-temperature drop-on-demand jetting

Drop-on-demand jetting of metals offers a fully digital manufacturing approach to surpass the limitations of the current generation powder-based additive manufacturing technologies. However, research on this topic has been restricted mainly to near-net shaping of relatively low melting temperature metals. Here it is proposed a novel approach to jet molten metals at high-temperatures (>1000 °C) to enable the direct digital additive fabrication of micro- to macro-scale objects. […] ... Read more

Marco Simonelli, Nesma Aboulkhair, Mircea Rasa, Mark East, Chris Tuck, Ricky Wildman, Otto Salomons, Richard Hague

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Micropore evolution in additively manufactured aluminum alloys under heat treatment and inter-layer rolling

Micropore evolution in additively manufactured aluminum alloys under heat treatment and inter-layer rolling

Additive manufacturing (AM) of aluminum alloy components has drawn broad attention from industrial customers in recent years. With the advantages of low cost and high deposition rate, wire + arc additive manufacturing (WAAM) has been recognized as a promising AM technology in producing large-scale aluminum alloy structural parts. However, the adverse effect of internal defects on mechanical properties has limited the application of WAAM aluminum alloys. Micropores, as one of the most harmfu... Read more

Jianglong Gu, Shouliang Yang, Minjie Gao, Jing Bai, Yuchun Zhai, Jialuo Ding

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The Fraunhofer Institute uses Avizo to explore a Peruvian mummy CT-scan

The Fraunhofer Institute uses Avizo to explore a Peruvian mummy CT-scan

As part of the Big Picture project, researchers at Fraunhofer IIS are working on three dimensions images of objects with great precision. In order to demonstrate the progress of the project, which has begun in February 2018, they made the 3d Xray-CT acquisition of a mummy from the Linden-Museum Stuttgart collection, probably from the 11th-15th century.
Modern measurement systems are producing increasingly large volumes of extremely complex data that must be stored, processed and convert... Read more

Prof. Dr. Tomas Sauer

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Aging of a Pt/Al2O3 exhaust gas catalyst monitored by quasi in situ X-ray micro computed tomography

Aging of a Pt/Al2O3 exhaust gas catalyst monitored by quasi in situ X-ray micro computed tomography

Catalyst aging effects were analyzed using X-ray absorption micro-computed tomography in combination with conventional characterization methods on various length scales ranging from nm to μm to gain insight into deactivation mechanisms.

For this purpose, a 4 wt% Pt/Al2O3 model exhaust gas catalyst was coated on a cordierite honeycomb and subjected to sequential thermal aging in static air at 950 °C for 4, 8, 12 and 24 hours. The ag... Read more

Georg Hofmann, Amélie Rochet, Elen Ogel, Maria Casapu, Stephan Ritter, Malte Ogurreck and Jan-Dierk Grunwaldt

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Juvenile Ovine Ex Vivo Larynges: Phonatory, Histologic, and Micro CT Based Anatomic Analyses

Juvenile Ovine Ex Vivo Larynges: Phonatory, Histologic, and Micro CT Based Anatomic Analyses

It is well known that the phonatory process changes during the life span. However, detailed investigations on potential factors concerned are rare. To deal with this issue, we performed extended biomechanical, macro anatomical, and histological analyses of the contributing laryngeal structures in ex vivo juvenile sheep models. Altogether twelve juvenile sheep larynges were analyzed within the phonatory experiments. Three different elongation levels and 16 different flow levels were applied to... Read more

Michael Döllinger, Olaf Wendler, Claus Gerstenberger, Tanja Grossmann, Marion Semmler, Hossein Sadeghi, and Markus Gugatschka

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Understanding the near-threshold crack growth behavior in an aluminum alloy by x-ray tomography

Understanding the near-threshold crack growth behavior in an aluminum alloy by x-ray tomography

The near-threshold behavior of long cracks is evaluated using pre-cracked flat dogbone specimens of a commercial aluminum alloy in two heat treatment states. Once the threshold was known, the crack initially introduced by cyclic compression was propagated under load control with approximately
constant range of the stress intensity factor at values close to the threshold values. The 3D morphology of the crack and the spatial distribution of the primary precipitates obtained by µ-CT were... Read more

Marcel Wicke, Angelika Brueckner-Foit, Tina Kirsten, Martina Zimmermann, Fatih Buelbuel, Hans-Juergen Christ

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Mechanical adaptation of trabecular bone morphology in the mammalian mandible

Mechanical adaptation of trabecular bone morphology in the mammalian mandible

Alveolar bone, together with the underlying trabecular bone, fulfils an important role in providing structural support against masticatory forces. Diseases such as osteoporosis or periodontitis cause alveolar bone resorption which weakens this structural support and is a major cause of tooth loss. However, the functional relationship between alveolar bone remodelling within the molar region and masticatory forces is not well understood. This study investigated this relationship by comparing m... Read more

Peter J. Watson, Laura C. Fitton, Carlo Meloro, Michael J. Fagan, Flora Gröning

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Analyzing the effects of powder and post-processing on porosity and properties of electron beam melted Ti-6Al-4V

Analyzing the effects of powder and post-processing on porosity and properties of electron beam melted Ti-6Al-4V

Metal additive manufacturing techniques such as the powder-bed systems are developing as a novel method for producing complex components.

This study uses synchrotron-based X-ray microtomography to investigate porosity in electron beam melted Ti-6Al-4V in the as-built and post-processed state for two different powders. The presence of gas porosity in the starting powder was shown to correlate to porosity in the as-built components. This porosity was observed to shrink after a hot isosta... Read more

Ross Cunningham, Andrea Nicolas, John Madsen, Eric Fodran, Elias Anagnostou, Michael D. Sangid & Anthony D. Rollett

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Flexible all-fiber electrospun supercapacitor

Flexible all-fiber electrospun supercapacitor

Electrospun all-fiber flexible supercapacitor with nanofiber electrodes/separator.

  • Increased graphitic degree with the addition of MnACAC and thermal decomposition.
  • Enhanced capacitive performance with the addition of MnO.
  • Quantified nanofiber alignment and increased bias with MnO over undoped fibers.
  • FIBSEM tomography of nanofibers showing MnO disitribution in carbon nanofibers.

We present an all-fiber flexible supercapacitor with compo... Read more

Xinhua Liu, Max Naylor Marlow, Samuel J. Cooper, Bowen Song, Xiaolong Chen, Nigel P. Brandon, Billy Wu

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Linking defects, hierarchical porosity generation and desalination performance in metal–organic frameworks

Linking defects, hierarchical porosity generation and desalination performance in metal–organic frameworks

Composite membranes with defective metal–organic frameworks (MOFs) connect the emerging fields of MOF topological modification, MOF-polymer interfacial engineering and composite material functionalization.

Although defective MOFs can be fabricated via thermal or chemical treatment, the relationship between hierarchical MOF structure and their performance in a polymeric membrane matrix has so far not been investigated. Here we show how a modula... Read more

Weibin Liang, Lin Li, Jingwei Hou, Nicholas D. Shepherd, Thomas D. Bennett, Deanna M. D'Alessandro and Vicki Chen

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Utilization of longitudinal ultrasound to quantify joint soft-tissue changes in a mouse model of posttraumatic osteoarthritis

Utilization of longitudinal ultrasound to quantify joint soft-tissue changes in a mouse model of posttraumatic osteoarthritis

Ultrasound could be a fast and cost-effective means of assessing joint changes in mouse models of posttraumatic osteoarthritis (PTOA). Such models are essential for understanding the biology of this degenerative joint disease and developing new treatments, but noninvasive methods of evaluating disease activity are lacking. Because ultrasound can visualize both joint space volumes and blood flow in the joints, it could provide an alternative to microscopic examination of tissue, assuming it ac... Read more

Hao Xu, Echoe M Bouta, Ronald W Wood, Edward M Schwarz, Yongjun Wang & Lianping Xing

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